Pharmacogenetics Research Clinic

Journal publications (since 2010)

2017

1. Esopenko C, Chow TW, Tartaglia MC, Bacopulos A, Kumar P, Binns MA, Kennedy JL, Müller DJ, Levine B. Cognitive and psychosocial function in retired professional hockey players. J Neurol Neurosurg Psychiatry. 2017 Apr 10.[Epub ahead of print] PMID: 28396361.

2. Zai CC, Tiwari AK, Chowdhury NI, Yilmaz Z, de Luca V, Müller DJ, Potkin SG, Lieberman JA, Meltzer HY, Voineskos AN, Remington G, Kennedy JL. Genetic study of neuregulin 1 and receptor tyrosine-protein kinase erbB-4 in tardive dyskinesia. World J Biol Psychiatry. 2017 Apr 10:1-5.[Epub ahead of print] PMID: 28394697.

3. Taylor DL, Tiwari AK, Lieberman JA, Potkin SG, Meltzer HY, Knight J, Remington G, Müller DJ, Kennedy JL. Pharmacogenetic Analysis of Functional Glutamate System Gene Variants and Clinical Response to Clozapine. Mol Neuropsychiatry. 2017 Feb;2(4):185-197.Epub 2016 Oct 12. PMID: 28277565.

4. Lanning R, Lett TA, Tiwari AK, Brandl EJ, de Luca V, Voineskos AN, Potkin SG, Lieberman JA, Meltzer HY, Müller DJ, Remington G, Kennedy JL, Zai CC. Association study between the neurexin-1 gene and tardive dyskinesia.Hum Psychopharmacol. 2017 Jan;32(1).PMID:28120489

5. Marshe VS, Maciukiewicz M, Rej S, Tiwari AK, Sibille E, Blumberger DM, Karp JF, Lenze EJ, Reynolds CF 3rd, Kennedy JL, Mulsant BH, Müller DJ.Norepinephrine Transporter Gene Variants and Remission From Depression With Venlafaxine Treatment in Older Adults.Am J Psychiatry. 2017 Jan 10. [Epub ahead of print]. PMID: 28068779

2016

1.Tiwari AK, Zhang D, Pouget JG, Zai CC, Chowdhury NI, Brandl EJ, Qin L, Freeman N, Lieberman JA, Meltzer HY, Kennedy JL, Müller DJ. Impact of Histamine Receptors H1 and H3 Polymorphisms on Antipsychotic-Induced Weight Gain. World J Biol Psychiatry. 2016 Nov 18:1-19. [Epub ahead of print] PMID: 27855565

2. Bousman CA, Müller DJ, Ng CH, Byron K, Berk M, Singh AB.Concordance between actual and pharmacogenetic predicted desvenlafaxine dose needed to achieve remission in major depressive disorder: a 10-week open-label study. Pharmacogenet Genomics. 2016 Oct 24.PMID:27779571

3. MacNeil RR, Müller DJ.Genetics of Common Antipsychotic-Induced Adverse Effects. Mol Neuropsychiatry. 2016 Jul;2(2):61-78. PMID: 27606321

4. Fonseka TM, Müller DJ, Kennedy SH. Inflammatory Cytokines and Antipsychotic-Induced Weight Gain: Review and Clinical Implications. Mol Neuropsychiatry. 2016 May;2(1):1-14. PMID:27606316

5. Kennedy SH, Lam RW, McIntyre RS, Tourjman SV, Bhat V, Blier P, Hasnain M, Jollant F, Levitt AJ, MacQueen GM, McInerney SJ, McIntosh D, Milev RV, Müller DJ, Parikh SV, Pearson NL, Ravindran AV, Uher R; CANMAT Depression Work Group.Canadian Network for Mood and Anxiety Treatments (CANMAT) 2016 Clinical Guidelines for the Management of Adults with Major Depressive Disorder: Section 3. Pharmacological Treatments.Can J Psychiatry. 2016 Sep;61(9):540-60. PMID:27486148

6. Lanning RK, Zai CC, Müller DJ.Pharmacogenetics of tardive dyskinesia: an updated review of the literature.Pharmacogenomics. 2016 Aug;17(12):1339-51.PMID:27469238

7. Brandl EJ, Lett TA, Chowdhury NI, Tiwari AK, Bakanidze G, Meltzer HY, Potkin SG, Lieberman JA, Kennedy JL, Müller DJ.The role of the ITIH3 rs2535629 variant in antipsychotic response.Schizophr Res. 2016 Jul 5. PMID:27396837

8. Rej S, Pira S, Marshe V, Do A, Elie D, Looper KJ, Herrmann N, Müller DJ. Molecular mechanisms in lithium-associated renal disease: a systematic review. Int Urol Nephrol. 2016 Jun 29.Review. PMID:27357223

9. Lam RW, Milev R, Rotzinger S, Andreazza AC, Blier P, Brenner C, Daskalakis ZJ, Dharsee M, Downar J, Evans KR, Farzan F, Foster JA, Frey BN, Geraci J, Giacobbe P, Feilotter HE, Hall GB, Harkness KL, Hassel S, Ismail Z, Leri F, Liotti M, MacQueen GM, McAndrews MP, Minuzzi L, Müller DJ, Parikh SV, Placenza FM, Quilty LC, Ravindran AV, Salomons TV, Soares CN, Strother SC, Turecki G, Vaccarino AL, Vila-Rodriguez F, Kennedy SH; CAN-BIND Investigator Team. Discovering biomarkers for antidepressant response: protocol from the Canadian biomarker integration network in depression (CAN-BIND) and clinical characteristics of the first patient cohort.BMC Psychiatry. 2016 Apr 16;16(1):105.PMID:27084692.

10. Bosche B, Molcanyi M, Noll T, Rej S, Zatschler B, Doeppner TR, Hescheler J, Müller DJ, Macdonald RL, Härtel FV.A differential impact of lithium on endothelium-dependent but not on endothelium-independent vessel relaxation.Prog Neuropsychopharmacol Biol Psychiatry. 2016 Jun 3;67:98-106.PMID:26875501

11.Taylor DL, Tiwari AK, Lieberman JA, Potkin SG, Meltzer HY, Knight J, Remington G, Müller DJ, Kennedy JL.Genetic association analysis of N-methyl-d-aspartate receptor subunit gene GRIN2B and clinical response to clozapine.Hum Psychopharmacol. 2016 Mar;31(2):121-34. Epub 2016 Feb 15.PMID:26876050

12. Huang E, Zai CC, Lisoway A, Maciukiewicz M, Felsky D, Tiwari AK, Bishop JR, Ikeda M, Molero P, Ortuno F, Porcelli S, Samochowiec J, Mierzejewski P, Gao S, Crespo-Facorro B, Pelayo-Terán JM, Kaur H, Kukreti R, Meltzer HY, Lieberman JA, Potkin SG, Müller DJ, Kennedy JL.Catechol-O-Methyltransferase Val158Met Polymorphism and Clinical Response to Antipsychotic Treatment in Schizophrenia and Schizo-Affective Disorder Patients: a Meta-Analysis.Int J Neuropsychopharmacol. 2016 Jan 8. PMID:26745992

2015

1. Huang E, Maciukiewicz M, Zai CC, Tiwari AK, Li J, Potkin SG, Lieberman JA, Meltzer HY, Müller DJ, Kennedy JL. Preliminary evidence for association of genome-wide significant DRD2 schizophrenia risk variant with clozapine response.Pharmacogenomics. 2015 Dec 15. PMID:26666695.

2.Carlier N, Marshe VS, Cmorejova J, Davis C, Müller DJ. Genetic Similarities between Compulsive Overeating and Addiction Phenotypes: A Case for "Food Addiction"? Curr Psychiatry Rep. 2015 Dec;17(12):96. PMID: 26478196.

3.Sriretnakumar V, Huang E, Müller DJ. Pharmacogenetics of clozapine treatment response and side-effects in schizophrenia: an update. Expert Opin Drug Metab Toxicol. 2015 Nov;11(11):1709-31. Epub 2015 Sep 12. PMID: 26364648.

4.Maciukiewicz M, Marshe VS, Tiwari AK, Fonseka TM, Freeman N, Rotzinger S, Foster JA, Kennedy JL, Kennedy SH, Müller DJ. Genetic variation in IL-1β, IL-2, IL-6, TSPO and BDNF and response to duloxetine or placebo treatment in major depressive disorder. Pharmacogenomics. 2015 Nov;16(17):1919-29. Epub 2015 Nov 10. PMID: 26556688.

5. Walden LM, Brandl EJ, Changasi A, Sturgess JE, Soibel A, Notario JF, Cheema S, Braganza N, Marshe VS, Freeman N, Tiwari AK, Kennedy JL, Müller DJ. Physicians' opinions following pharmacogenetic testing for psychotropic medication. Psychiatry Res. 2015 Oct 30;229(3):913-8. Epub 2015 Aug 7. PMID: 26298505.

6. Kalman LV, Agúndez JA, Appell ML, Black JL, Bell GC, Boukouvala S, Bruckner C, Bruford E, Bruckner C, Caudle K, Coulthard S, Daly AK, Del Tredici AL, den Dunnen JT, Drozda K, Everts R, Flockhart D, Freimuth R, Gaedigk A, Hachad H, Hartshorne T, Ingelman-Sundberg M, Klein TE, Lauschke VM, Maglott DR, McLeod HL, McMillin GA, Meyer UA, Müller DJ, Nickerson DA, Oetting WS, Pacanowski M, Pratt VM, Relling MV, Roberts A, Rubinstein WS, Sangkuhl K, Schwab M, Scott SA, Sim SC, Thirumaran RK, Toji LH, Tyndale R, van Schaik RH, Whirl-Carrillo M, Yeo KJ, Zanger UM. Pharmacogenetic Allele Nomenclature: International Workgroup Recommendations for Test Result Reporting. Clin Pharmacol Ther. 2015 Oct 19. [Epub ahead of print] Review. PMID: 26479518.

7. Tiwari AK, Brandl EJ, Zai CC, Goncalves VF, Chowdhury NI, Freeman N, Lieberman JA, Meltzer HY, Kennedy JL, Müller DJ. Association of orexin receptor polymorphisms with antipsychotic-induced weight gain. World J Biol Psychiatry. 2015 Oct 8:1-9. [Epub ahead of print] PMID: 26447462.

8. Shams TA, Foussias G, Zawadzki JA, Marshe VS, Siddiqui I, Müller DJ, Wong AH. The Effects of Video Games on Cognition and Brain Structure: Potential Implications for Neuropsychiatric Disorders. Curr Psychiatry Rep. 2015 Sep;17(9):71. PMID: 26216589.

9. Brandl EJ, Tiwari AK, Zai CC, Nurmi EL, Chowdhury NI, Arenovich T, Sanches M, Goncalves VF, Shen JJ, Lieberman JA, Meltzer HY, Kennedy JL, Müller DJ. Genome-wide association study on antipsychotic-induced weight gain in the CATIE sample. Pharmacogenomics J. 2015 Sep 1. [Epub ahead of print] PMID: 26323598.

10. Hicks JK, Bishop JR, Sangkuhl K, Müller DJ, Ji Y, Leckband SG, Leeder JS, Graham RL, Chiulli DL, LLerena A, Skaar TC, Scott SA, Stingl JC, Klein TE, Caudle KE, Gaedigk A; Clinical Pharmacogenetics Implementation Consortium. Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2D6 and CYP2C19 Genotypes and Dosing of Selective Serotonin Reuptake Inhibitors. Clin Pharmacol Ther. 2015 Aug;98(2):127-34. Epub 2015 Jun 29.PMID: 25974703.

11. Zai CC, Tiwari AK, Chowdhury NI, Brandl EJ, Shaikh SA, Freeman N, Lieberman JA, Meltzer HY, Müller DJ, Kennedy JL. Association study of GABAA α2 receptor subunit gene variants in antipsychotic-associated weight gain. J Clin Psychopharmacol. 2015 Feb;35(1):7-12. PMID: 25514066.

12. Schmack K, Rössler H, Sekutowicz M, Brandl EJ, Müller DJ, Petrovic P, Sterzer P. Linking unfounded beliefs to genetic dopamine availability. Front Hum Neurosci. 2015 Sep 30;9:521. eCollection 2015. PMID: 26483654.

13. Domschke K, Müller DJ, Serretti A. Personalized therapies in psychiatry: promises, pitfalls and perspectives. J Neural Transm (Vienna). 2015 Jan;122(1):1-3. PMID: 25476585.

14. Brandl EJ, Chowdhury NI, Tiwari AK, Lett TA, Meltzer HY, Kennedy JL, Müller DJ. Genetic variation in CYP3A43 is associated with response to antipsychotic medication. J Neural Transm (Vienna). 2015 Jan;122(1):29-34. Epub 2014 Aug 24. PMID: 25150845.

15. Pouget JG, Gonçalves VF, Nurmi EL, P Laughlin C, Mallya KS, McCracken JT, Aman MG, McDougle CJ, Scahill L, Misener VL, Tiwari AK, Zai CC, Brandl EJ, Felsky D, Leung AQ, Lieberman JA, Meltzer HY, Potkin SG, Niedling C, Steimer W, Leucht S, Knight J, Müller DJ, Kennedy JL. Investigation of TSPO variants in schizophrenia and antipsychotic treatment outcomes. Pharmacogenomics. 2015 Jan;16(1):5-22. PMID: 25560467.

16. Fonseka TM, Tiwari AK, Gonçalves VF, Lieberman JA, Meltzer HY, Goldstein BI, Kennedy JL, Kennedy SH, Müller DJ. The role of genetic variation across IL-1β, IL-2, IL-6, and BDNF in antipsychotic-induced weight gain. World J Biol Psychiatry. 2015 Jan;16(1):45-56.PMID:25560300.

2014

1.Pouget JG, Shams TA, Tiwari AK, Müller DJ. Pharmacogenetics and outcome with antipsychotic drugs. Dialogues Clin Neurosci. 2014 Dec;16(4):555-66. Review. PMID: 25733959; PubMed Central PMCID: PMC4336924.

2. Fonseka TM, Richter MA, Müller DJ. Second generation antipsychotic-induced obsessive-compulsive symptoms in schizophrenia: a review of the experimental literature. Curr Psychiatry Rep. 2014 Nov;16(11):510. Review. PMID: 25256097.

3. Brandl EJ, Tiwari AK, Zai CC, Chowdhury NI, Lieberman JA, Meltzer HY, Kennedy JL, Müller DJ. No evidence for a role of the peroxisome proliferator-activated receptor gamma (PPARG) and adiponectin (ADIPOQ) genes in antipsychotic-induced weight gain. Psychiatry Res. 2014 Oct 30;219(2):255-60. Epub 2014 May 28. PMID: 24953421.

4. Shams TA, Müller DJ. Antipsychotic induced weight gain: genetics, epigenetics, and biomarkers reviewed. Curr Psychiatry Rep. 2014 Oct;16(10):473.Review. PMID: 25138234.

5. Gebara MA, Shea ML, Lipsey KL, Teitelbaum SL, Civitelli R, Müller DJ, Reynolds CF 3rd, Mulsant BH, Lenze EJ. Depression, antidepressants, and bone health in older adults: a systematic review. J Am Geriatr Soc. 2014 Aug;62(8):1434-41. Epub 2014 Jul 15. R PMID: 25039259.

6. Gagliano SA, Tiwari AK, Freeman N, Lieberman JA, Meltzer HY, Kennedy JL, Knight J, Müller DJ. Protein kinase cAMP-dependent regulatory type II beta (PRKAR2B) gene variants in antipsychotic-induced weight gain. Hum Psychopharmacol. 2014 Jul;29(4):330-5. Epub 2014 Apr 16. PMID: 24737441.

7. Kao AC, Rojnic Kuzman M, Tiwari AK, Zivkovic MV, Chowdhury NI, Medved V, Kekin I, Zai CC, Lieberman JA, Meltzer HY, Bozina T, Bozina N, Kennedy JL, Sertic J, Müller DJ. Methylenetetrahydrofolate reductase gene variants and antipsychotic-induced weight gain and metabolic disturbances. J Psychiatr Res. 2014 Jul;54:36-42. Epub 2014 Mar 21. PMID: 24725652.

8. Todd RM, Müller DJ, Palombo DJ, Robertson A, Eaton T, Freeman N, Levine B, Anderson AK. Deletion variant in the ADRA2B gene increases coupling between emotional responses at encoding and later retrieval of emotional memories. Neurobiol Learn Mem. 2014 Jul;112:222-9. Epub 2013 Oct 19. PMID: 24149058.

9. Garfield LD, Müller DJ, Kennedy JL, Mulsant BH, Reynolds CF 3rd, Teitelbaum SL, Civitelli R, Dixon D, Todorov AA, Lenze EJ. Genetic variation in the serotonin transporter and HTR1B receptor predicts reduced bone formation during serotonin reuptake inhibitor treatment in older adults. World J Biol Psychiatry. 2014 Jul;15(5):404-10. Epub 2013 Sep 30. PMID: 24074042.

10. Zai G, Brandl EJ, Müller DJ, Richter MA, Kennedy JL. Pharmacogenetics of antidepressant treatment in obsessive-compulsive disorder: an update and implications for clinicians. Pharmacogenomics. 2014 Jun;15(8):1147-57. Erratum in: Pharmacogenomics. 2015;16(6):668. PPMID: 25084207.

11. Gonçalves VF, Zai CC, Tiwari AK, Brandl EJ, Derkach A, Meltzer HY, Lieberman JA, Müller DJ, Sun L, Kennedy JL. A hypothesis-driven association study of 28 nuclear-encoded mitochondrial genes with antipsychotic-induced weight gain in schizophrenia. Neuropsychopharmacology. 2014 May;39(6):1347-54. Epub 2013 Nov 7. PMID: 24196945.

12. Tiwari AK, Need AC, Lohoff FW, Zai CC, Chowdhury NI, Müller DJ, Putkonen A, Repo-Tiihonen E, Hallikainen T, Yağcıoğlu AE, Tiihonen J, Kennedy JL, Meltzer HY. Exome sequence analysis of Finnish patients with clozapine-induced agranulocytosis. Mol Psychiatry. 2014 Apr;19(4):403-5. Epub 2013 Jun 11. PMID: 23752246.

13. Brandl EJ, Tiwari AK, Zhou X, Deluce J, Kennedy JL, Müller DJ, Richter MA. Influence of CYP2D6 and CYP2C19 gene variants on antidepressant response in obsessive-compulsive disorder. Pharmacogenomics J. 2014 Apr;14(2):176-81. Epub 2013 Apr 2. PMID: 23545896.

14. Chowdhury NI, Souza RP, Tiwari AK, Brandl EJ, Sicard M, Meltzer HY, Lieberman JA, Kennedy JL, Müller DJ. Investigation of melanocortin system gene variants in antipsychotic-induced weight gain. World J Biol Psychiatry. 2014 Apr;15(3):251-8.Epub 2014 Feb 24. PMID: 24564533.

15. Olgiati P, Mandelli L, Alberti S, Lia L, Serretti A, Tiwari AK, Jain U, Kennedy JL, Müller DJ. Role of synaptosome-related (SNARE) genes in adults with attention deficit hyperactivity disorder. Psychiatry Res. 2014 Mar 30;215(3):799-800. Epub 2013 Oct 28. PubMed PMID: 24176595.

16. Brandl EJ, Tiwari AK, Chowdhury NI, Zai CC, Lieberman JA, Meltzer HY, Kennedy JL, Müller DJ. Genetic variation in the GCG and in the GLP1R genes and antipsychotic-induced weight gain. Pharmacogenomics. 2014 Mar;15(4):423-31. PMID: 24624910.

17.Brandl EJ, Kennedy JL, Müller DJ. Pharmacogenetics of antipsychotics. Can J Psychiatry. 2014 Feb;59(2):76-88. PMID: 24881126.

19. Caudle KE, Klein TE, Hoffman JM, Muller DJ, Whirl-Carrillo M, Gong L, McDonagh EM, Sangkuhl K, Thorn CF, Schwab M, Agundez JA, Freimuth RR, Huser V, Lee MT, Iwuchukwu OF, Crews KR, Scott SA, Wadelius M, Swen JJ, Tyndale RF, Stein CM, Roden D, Relling MV, Williams MS, Johnson SG. Incorporation of pharmacogenomics into routine clinical practice: the Clinical Pharmacogenetics Implementation Consortium (CPIC) guideline development process. Curr Drug Metab. 2014 Feb;15(2):209-17. PMID: 24479687.

20. Drozda K, Müller DJ, Bishop JR. Pharmacogenomic testing for neuropsychiatric drugs: current status of drug labeling, guidelines for using genetic information, and test options. Pharmacotherapy. 2014 Feb;34(2):166-84.PMID: 24523097.

21. Heinz A, Müller DJ, Krach S, Cabanis M, Kluge UP. The uncanny return of the race concept. Front Hum Neurosci. 2014 Nov 4;8:836. eCollection 2014. PMID: 25408642.

22. Pouget JG, Müller DJ. Pharmacogenetics of antipsychotic treatment in schizophrenia. Methods Mol Biol. 2014;1175:557-87. PMID: 25150876.

23. Shing EC, Tiwari AK, Brandl EJ, Zai CC, Lieberman JA, Meltzer HY, Kennedy JL, Müller DJ. Fat mass- and obesity-associated (FTO) gene and antipsychotic-induced weight gain: an association study. Neuropsychobiology. 2014;69(1):59-63. Epub 2014 Jan 30. PMID: 24481458.

2013

1. Kao AC, Müller DJ. Genetics of antipsychotic-induced weight gain: update and current perspectives. Pharmacogenomics. 2013 Dec;14(16):2067-83.PubMed PMID: 24279860.

2. Gonçalves VF, Zai CC, Tiwari AK, Brandl EJ, Derkach A, Meltzer HY, Lieberman JA, Müller DJ, Sun L, Kennedy JL. A hypothesis-driven association study of 28 nuclear-encoded mitochondrial genes with antipsychotic-induced weight gain in schizophrenia. Neuropsychopharmacology. 2014 May;39(6):1347-54. Epub 2013 Nov 7. PubMed PMID: 24196945.

3. Olgiati P, Mandelli L, Alberti S, Lia L, Serretti A, Tiwari AK, Jain U, Kennedy JL, Müller DJ. Role of synaptosome-related (SNARE) genes in adults with attention deficit hyperactivity disorder. Psychiatry Res. 2014 Mar 30;215(3):799-800. Epub 2013 Oct 28. PMID: 24176595.

4. Müller DJ, Kekin I, Kao AC, Brandl EJ. Towards the implementation of CYP2D6 and CYP2C19 genotypes in clinical practice: update and report from a pharmacogenetic service clinic. Int Rev Psychiatry. 2013 Oct;25(5):554-71.PMID: 24151801.

5. Todd RM, Müller DJ, Palombo DJ, Robertson A, Eaton T, Freeman N, Levine B, Anderson AK. Deletion variant in the ADRA2B gene increases coupling between emotional responses at encoding and later retrieval of emotional memories. Neurobiol Learn Mem. 2014 Jul;112:222-9.PubMed PMID: 24149058.

6. Zai CC, Tiwari AK, Mazzoco M, de Luca V, Müller DJ, Shaikh SA, Lohoff FW, Freeman N, Voineskos AN, Potkin SG, Lieberman JA, Meltzer HY, Remington G, Kennedy JL. Association study of the vesicular monoamine transporter gene SLC18A2 with tardive dyskinesia. J Psychiatr Res. 2013 Nov;47(11):1760-5. Epub 2013 Sep 6.PMID: 24018103.

7. Müller DJ, Chowdhury NI, Zai CC. The pharmacogenetics of antipsychotic-induced adverse events. Curr Opin Psychiatry. 2013 Mar;26(2):144-50.PMID: 23370274.

8. Brandl EJ, Tiwari AK, Lett TA, Shaikh SA, Lieberman JA, Meltzer HY, Kennedy JL, Müller DJ. Exploratory study on association of genetic variation in TBC1D1 with antipsychotic-induced weight gain. Hum Psychopharmacol. 2013 Mar;28(2):183-7. Epub 2013 Jan 30.PMID: 23364847.

9. Tiwari AK, Brandl EJ, Weber C, Likhodi O, Zai CC, Hahn MK, Lieberman JA, Meltzer HY, Kennedy JL, Müller DJ. Association of a functional polymorphism in neuropeptide Y with antipsychotic-induced weight gain in schizophrenia patients. J Clin Psychopharmacol. 2013 Feb;33(1):11-7. PMID: 23277265.

10. Tiwari AK, Zai CC, Sajeev G, Arenovich T, Müller DJ, Kennedy JL. Analysis of 34 candidate genes in bupropion and placebo remission. Int J Neuropsychopharmacol. 2013 May;16(4):771-81. doi: 10.1017/S1461145712000843. Epub 2012 Sep 4. PubMed PMID: 22947179.

2012

1. Müller DJ, Brandl EJ, Hwang R, Tiwari AK, Sturgess JE, Zai CC, Lieberman JA, Kennedy JL, Richter MA. The AmpliChip® CYP450 test and response to treatment in schizophrenia and obsessive compulsive disorder: a pilot study and focus on cases with abnormal CYP2D6 drug metabolism. Genet Test Mol Biomarkers. 2012 Aug;16(8):897-903.PMID: 22775532.

2. Gvozdic K, Brandl EJ, Taylor DL, Müller DJ. Genetics and personalized medicine in antidepressant treatment. Curr Pharm Des. 2012;18(36):5853-78. PMID: 22681166.

3. Zai GC, Zai CC, Chowdhury NI, Tiwari AK, Souza RP, Lieberman JA, Meltzer HY, Potkin SG, Müller DJ, Kennedy JL. The role of brain-derived neurotrophic factor (BDNF) gene variants in antipsychotic response and antipsychotic-induced weight gain. Prog Neuropsychopharmacol Biol Psychiatry. 2012 Oct 1;39(1):96-101. Epub 2012 May 27.PMID: 22642961.

4. Brandl EJ, Frydrychowicz C, Tiwari AK, Lett TA, Kitzrow W, Büttner S, Ehrlich S, Meltzer HY, Lieberman JA, Kennedy JL, Müller DJ, Puls I. Association study of polymorphisms in leptin and leptin receptor genes with antipsychotic-induced body weight gain. Prog Neuropsychopharmacol Biol Psychiatry. 2012 Aug 7;38(2):134-41. Epub 2012 Mar 8. PMID: 22426215.

5. Chowdhury NI, Tiwari AK, Souza RP, Zai CC, Shaikh SA, Chen S, Liu F, Lieberman JA, Meltzer HY, Malhotra AK, Kennedy JL, Müller DJ. Genetic association study between antipsychotic-induced weight gain and the melanocortin-4 receptor gene. Pharmacogenomics J. 2013 Jun;13(3):272-9 Epub 2012 Feb 7. PMID: 22310352.

6. Souza RP, Tiwari AK, Chowdhury NI, Ceddia RB, Lieberman JA, Meltzer HY, Kennedy JL, Müller DJ. Association study between variants of AMP-activated protein kinase catalytic and regulatory subunit genes with antipsychotic-induced weight gain. J Psychiatr Res. 2012 Apr;46(4):462-8. Epub 2012 Feb 2.PMID: 22305490.

7. Shamy MC, Zai C, Basile VS, Kennedy JL, Müller DJ, Masellis M. Ethical and Policy Considerations in the Application of Pharmacogenomic Testing for Tardive Dyskinesia: Case Study of the Dopamine D3 Receptor. Curr Pharmacogenomics Person Med. 2011 Jun 1;9(2):94-101. PMID: 22282718.

8. Brandl EJ, Müller DJ, Richter MA. Pharmacogenetics of obsessive-compulsive disorders. Pharmacogenomics. 2012 Jan;13(1):71-81.PMID: 22176623.

9. Lett TA, Wallace TJ, Chowdhury NI, Tiwari AK, Kennedy JL, Müller DJ. Pharmacogenetics of antipsychotic-induced weight gain: review and clinical implications. Mol Psychiatry. 2012 Mar;17(3):242-66.Epub 2011 Sep 6. PMID: 21894153.

2011

1.Lett TA, Tiwari AK, Meltzer HY, Lieberman JA, Potkin SG, Voineskos AN, Kennedy JL, Müller DJ. The putative functional rs1045881 marker of neurexin-1 in schizophrenia and clozapine response. Schizophr Res. 2011 Nov;132(2-3):121-4.Epub 2011 Sep 3. PMID: 21890328.

2. De Luca V, Souza RP, Viggiano E, Sickert L, Teo C, Zai C, Tiwari AK, Müller DJ, Lieberman JA, Volavka J, Meltzer HY, Kennedy JL. Genetic interactions in the adrenergic system genes: analysis of antipsychotic-induced weight gain. Hum Psychopharmacol. 2011 Aug;26(6):386-91. Epub 2011 Aug 8.PMID: 21823169.

3. Lett TA, Zai CC, Tiwari AK, Shaikh SA, Likhodi O, Kennedy JL, Müller DJ. ANK3, CACNA1C and ZNF804A gene variants in bipolar disorders and psychosis subphenotype. World J Biol Psychiatry. 2011 Aug;12(5):392-7.Epub 2011 Jul 18. PMID: 21767209.

4. Voineskos AN, Lett TA, Lerch JP, Tiwari AK, Ameis SH, Rajji TK, Müller DJ, Mulsant BH, Kennedy JL. Neurexin-1 and frontal lobe white matter: an overlapping intermediate phenotype for schizophrenia and autism spectrum disorders. PLoS One. 2011;6(6):e20982. Epub 2011 Jun 8. PMID: 21687627.

5. Müller DJ, Zai CC, Shinkai T, Strauss J, Kennedy JL. Association between the DAOA/G72 gene and bipolar disorder and meta-analyses in bipolar disorder and schizophrenia. Bipolar Disord. 2011 Mar;13(2):198-207. PMID: 21443574.

6. Sturgess JE, George TP, Kennedy JL, Heinz A, Müller DJ. Pharmacogenetics of alcohol, nicotine and drug addiction treatments. Addict Biol. 2011 Jul;16(3):357-76.Epub 2011 Mar 1. PMID: 21362114.

7. Hwang R, Souza RP, Tiwari AK, Zai CC, Müller DJ, Potkin SG, Lieberman JA, Meltzer HY, Kennedy JL. Gene-gene interaction analyses between NMDA receptor subunit and dopamine receptor gene variants and clozapine response. Pharmacogenomics. 2011 Feb;12(2):277-91. PMID: 21332319.

8. Tiwari AK, Zai CC, Likhodi O, Voineskos AN, Meltzer HY, Lieberman JA, Potkin SG, Remington G, Müller DJ, Kennedy JL. Association study of cannabinoid receptor 1 (CNR1) gene in tardive dyskinesia. Pharmacogenomics J. 2012 Jun;12(3):260-6.Epub 2011 Jan 25. PMID: 21266946.

9. Wallace TJ, Zai CC, Brandl EJ, Müller DJ. Role of 5-HT(2C) receptor gene variants in antipsychotic-induced weight gain. Pharmgenomics Pers Med. 2011;4:83-93. Epub 2011 Aug 18. PMID: 232260551.

2010

1. Sicard MN, Zai CC, Tiwari AK, Souza RP, Meltzer HY, Lieberman JA, Kennedy JL, Müller DJ. Polymorphisms of the HTR2C gene and antipsychotic-induced weight gain: an update and meta-analysis. Pharmacogenomics. 2010 Nov;11(11):1561-71. PMID: 21121776.

2. Tiwari AK, Zai CC, Müller DJ, Kennedy JL. Genetics in schizophrenia: where are we and what next? Dialogues Clin Neurosci. 2010;12(3):289-303. PMID: 20954426.

3. Tiwari AK, Rodgers JB, Sicard M, Zai CC, Likhodi O, Freeman N, Meltzer HY, Lieberman JA, Kennedy JL, Müller DJ. Association study of polymorphisms in cholecystokinin gene and its receptors with antipsychotic induced weight gain in schizophrenia patients. Prog Neuropsychopharmacol Biol Psychiatry. 2010 Dec 1;34(8):1484-90. Epub 2010 Aug 20. PMID: 20732371.

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